![Project 1: Therapeutic Potential of Kappa Opioid Receptor Antagonists in the Treatment of Depression (Chavkin) | Conte Center Project 1: Therapeutic Potential of Kappa Opioid Receptor Antagonists in the Treatment of Depression (Chavkin) | Conte Center](http://depts.washington.edu/uwconte/wp-content/uploads/figure-2.jpeg)
Project 1: Therapeutic Potential of Kappa Opioid Receptor Antagonists in the Treatment of Depression (Chavkin) | Conte Center
![LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders - ScienceDirect LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0028390813004280-gr3.jpg)
LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders - ScienceDirect
![Project 1: Therapeutic Potential of Kappa Opioid Receptor Antagonists in the Treatment of Depression (Chavkin) | Conte Center Project 1: Therapeutic Potential of Kappa Opioid Receptor Antagonists in the Treatment of Depression (Chavkin) | Conte Center](http://depts.washington.edu/uwconte/wp-content/uploads/Charley-2.jpg)
Project 1: Therapeutic Potential of Kappa Opioid Receptor Antagonists in the Treatment of Depression (Chavkin) | Conte Center
![A Practical Approach for the Management of the Mixed Opioid Agonist- Antagonist Buprenorphine During Acute Pain and Surgery - Mayo Clinic Proceedings A Practical Approach for the Management of the Mixed Opioid Agonist- Antagonist Buprenorphine During Acute Pain and Surgery - Mayo Clinic Proceedings](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/39676bff-77c0-488b-a71d-5935f5d5de3c/gr1.jpg)
A Practical Approach for the Management of the Mixed Opioid Agonist- Antagonist Buprenorphine During Acute Pain and Surgery - Mayo Clinic Proceedings
![Dynorphin-kappa opioid receptor activity in the central amygdala modulates binge-like alcohol drinking in mice | Neuropsychopharmacology Dynorphin-kappa opioid receptor activity in the central amygdala modulates binge-like alcohol drinking in mice | Neuropsychopharmacology](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41386-018-0294-3/MediaObjects/41386_2018_294_Fig1_HTML.png)
Dynorphin-kappa opioid receptor activity in the central amygdala modulates binge-like alcohol drinking in mice | Neuropsychopharmacology
![Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors* - Journal of Biological Chemistry Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors* - Journal of Biological Chemistry](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/45b3ba2c-74f9-47f6-9573-b38274bd67d1/gr2.jpg)
Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors* - Journal of Biological Chemistry
![Project 1: Therapeutic Potential of Kappa Opioid Receptor Antagonists in the Treatment of Depression (Chavkin) | Conte Center Project 1: Therapeutic Potential of Kappa Opioid Receptor Antagonists in the Treatment of Depression (Chavkin) | Conte Center](http://depts.washington.edu/uwconte/wp-content/uploads/figure-1.jpeg)
Project 1: Therapeutic Potential of Kappa Opioid Receptor Antagonists in the Treatment of Depression (Chavkin) | Conte Center
![Project 1: Therapeutic Potential of Kappa Opioid Receptor Antagonists in the Treatment of Depression (Chavkin) | Conte Center Project 1: Therapeutic Potential of Kappa Opioid Receptor Antagonists in the Treatment of Depression (Chavkin) | Conte Center](http://depts.washington.edu/uwconte/wp-content/uploads/figure-3.jpeg)